86
Cobalt-catalyzed regio- and diastereoselective carbocyclization/arylation of 1,5-bisallenes
85
Discovery of Tetrahydro Tanshinone I as a Naturally Occurring Covalent Pan-Inhibitor Against Gut Microbial Bile Salt Hydrolases
84
Pyridine-Boryl Radical-Catalyzed [3 + 2] Cycloadditions of Alkyne-Tethered Cyclopropyl Ketones
83
High-throughput modular click chemistry synthesis of catechol derivatives as covalent inhibitors of SARS-CoV-2 3CLpro
82
Recent progress in asymmetric rearrangement reactions mediated by chiral Brønsted acids
81
Enantioselective Reductive Cyclization of Alkynyl-Tethered Cyclohexadienones Catalyzed by Rhodium Complexes
80
N-Heterocyclic Carbene-Catalyzed Formal Intramolecular [3 + 2] Annulations of Cyclohexadienone-Tethered Ynals
79
Identification of benzo[b]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors
78
Discovery of natural catechol derivatives as covalent SARS-CoV-2 3CLpro inhibitors
77
Advancements and reviews in research of chiral drugs derived from traditional Chinese herbal medicine
76
Rhodium(III)-catalyzed diastereo- and enantioselective hydrosilylation/cyclization reaction of cyclohexadienone-tethered α,β-unsaturated aldehydes
75
A practical preparation of bicyclic boronates via metal-free heteroatom-directed alkenyl sp2-C‒H borylation
74
Discovery of highly potent covalent SARS-CoV-2 3CLpro inhibitors bearing 2-sulfoxyl-1,3,4-oxadiazole scaffold for combating COVID-19
73
Cobalt-Catalyzed Chemo- and Stereoselective Arylative Carbocyclization of 1,6-Allenynes
72
Copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of 1,3-enynes and azomethine ylides
71
Nature-Inspired Catalytic Asymmetric Rearrangement of Cyclopropylcarbinyl Cation
70
A Highly Enantioselective Homoenolate Michael Addition/Esterification Sequence of Cyclohexadienone-Tethered Enals via NHC Catalysis
69
Thiourea-Promoted Cascade Dihalogenation-Cyclization of Cyclohexadienone-Containing 1,6-Enynes
68
Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy
67
A Practical and Scalable Preparation of Lusianthridin
66
Novel inhibitors of the STAT3 signaling pathway: an updated patent review (2014-present)
65
Discovery of PHGDH inhibitors by virtual screening and preliminary structure-activity relationship study
64
Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19
63
Catalyst-Controlled Diastereoselectivity Switch in the Asymmetric [3 + 2] Annulation of Isatin-Derived MBH Carbonates and 5-Alkenylthiazol-4(5H)-ones
62
Diastereo- and enantioselective rhodium(III)-catalyzed reductive cyclization of cyclohexadienone-containing 1,6-dienes
61
Rhodium(III)-Catalyzed Asymmetric Reductive Cyclization of Cyclohexadienone-Containing 1,6-Dienes via an Anti-Michael/Michael Cascade Process
60
A retrospective overview of PHGDH and its inhibitors for regulating cancer metabolism
59
Muscone derivative ZM-32 inhibits breast tumor angiogenesis by suppressing HuR-mediated VEGF and MMP9 expression
58
One-Pot Preparation of Tricyclo[5.2.2.04,9]undecanes via Cu-Catalyzed Asymmetric Carboboration of Cyclohexadienone-Tethered Allenes
57
Palladium-catalyzed desymmetric [2+2+2] cycloaddition of 1,6-enyne and alkyne
56
Rhodium(III)-catalyzed asymmetric carboboration of heterobicyclic alkenes
55
Copper(I)-catalyzed asymmetric 1,6-conjugate allylation
54
Identification of novel STAT3 inhibitors bearing 2-acetyl-7-phenylamino benzofuran scaffold for antitumour study
53
One-Pot Preparation of Bridged Tricyclic and Fused Tetracyclic Scaffolds via Rhodium(III)-Catalyzed Asymmetric Borylative Cyclization
52
Synthesis of Chiral anti-1,2-Diamine Derivatives through Copper(I)-Catalyzed Asymmetric α-Addition of Ketimines to Aldimines
51
Synthesis of Decahydrocyclobuta[cd]indene Skeleton: Rhodium(III)‐Catalyzed Hydroarylation and Relay Thiophene‐Promoted Intramolecular [2+2] Cycloaddition
50
Copper(I)-catalyzed Diastereo- and Enantio-selective Construction of Optically Pure Exocyclic Allenes
49
Enantioselective [3+2] annulation of isatin-derived MBH-carbonates and 3-nitroindoles enabled by a bifunctional DMAP-thiourea
48
An Unconventional trans-exo-Selective Cyclization of Alkyne-Tethered Cyclohexadienones Initiated by Rhodium(III)-Catalyzed C–H Activation via Insertion Relay
47
Design, Synthesis and Biological Evaluation of Novel Potent STAT3 Inhibitors Based on BBI608 for Cancer Therapy
46
One-Pot Preparation of 9,10-Dihydrophenanthrenes Initiated by Rhodium(III)-Catalyzed C−H Activation and Relay Diels−Alder Reaction
45
Nickel(II)-Catalyzed Addition of Aryl-, Alkenyl-, and Alkylboronic Acids to Alkenylazaarenes
44
Rhodium(III)-Catalyzed Kinetic Resolution of Racemic 1,6-Dienes via Asymmetric Borylative Cyclization
43
Elucidation of the Structure of Pseudorubriflordilactone B by Chemical Synthesis
42
Neuroprotective effect of salvianolate on cerebral ischaemia-reperfusion injury in rats by inhibiting the Caspase-3 signal pathway
41
Activating Pronucleophiles with High pKa Values: Chiral Organo‐Superbases
40
Copper‐Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone‐Containing 1,6‐Dienes
39
Access to Aryl-Naphthaquinone Atropisomers via Phosphine-Catalyzed Atroposelective (4+2) Annulations of δ-Acetoxy Allenoates with 2-Hydroxyquinone Derivatives
38
Rhodium(III)-Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone-Containing 1,6-Dienes: An Experimental and DFT Study
37
Pd(0)-Catalyzed Cyclizative Phosphorylation of (Z)-1-Iodo-1,6-diene: Synthesis of Alkylphosphonate and Alkylthionophosphonate
36
Acetic Acid-Promoted Rhodium(III)-Catalyzed Hydroarylation of Terminal Alkynes
35
Highly Enantioselective Rhodium-Catalyzed Cross-Addition of Silylacetylenes to Cyclohexadienone-Tethered Internal Alkynes
34
Arylation/Intramolecular Conjugate Addition of 1,6-Enynes Enabled by Manganese(I)-Catalyzed C–H Bond Activation
33
A novel chiral DMAP–thiourea bifunctional catalyst catalyzed enantioselective Steglich and Black rearrangement reactions
32
Trisannulation of benzamides and cyclohexadienone-tethered 1,1-disubstituted allenes initiated by Cp*Rh(III)-catalyzed C–H activation
31
Copper-catalyzed asymmetric silylative cyclization of cyclohexadienone-containing 1,6-enynes
30
Facile Access to 1,5-Benzodiazepines via Amine-Promoted (4+3) Annulations of δ-Acetoxy Allenoates with o-Diaminobenzenes under Mild Conditions.
29
Efficient Access to cis-Hydrobenzo[b]oxepines: Rhodium(I)-Catalyzed Cyclization of Cyclohexadienone-Tethered o-Tolyl-Substituted Alkynes.
28
Bisannulation of Benzamides and Cyclohexadienone-Tethered Allenes Triggered by Cp*Rh(III)-Catalyzed C–H Activation and Relay Ene Reaction.
27
CuH-Catalyzed Asymmetric Intramolecular Reductive Coupling of Allenes to Enones.
26
Identification of an Imine Reductase for Asymmetric Reduction of Bulky Dihydroisoquinolines
25
Efficient access to cis-decalinol frameworks: copper(I)-catalyzed borylative cyclization of allene cyclohexanediones
24
Recent Progress on Cu-Catalyzed Conjugate Silylation to Unsaturated Compounds
23
Two phenyls are better than one or three: synthesis and application of terminal olefin-oxazoline (TOlefOx) ligands
22
Amine-promoted asymmetric [4+2] cycloadditions of α-acetoxymethyl allenoate and dual activated alkenes: stereoselective synthesis of poly-substituted cyclohexenes
21
Copper-catalyzed asymmetric allylation of chiral N-tert-butanesulfinyl imines: dual stereocontrol with nearly perfect diastereoselectivity
20
Efficient Access to Bicyclo[4.3.0]nonanes: Copper-Catalyzed Asymmetric Silylative Cyclization of Cyclohexadienone-Tethered Allenes
19
Recent Progress on Cu-Catalyzed Asymmetric Conjugate Borylation to α,β-Unsaturated Compounds
18
Copper(I)-catalyzed enantioselective hydroboration of cyclopropenes: facile synthesis of optically active cyclopropylboronates
17
Copper-Catalyzed Asymmetric Hydroboration of alpha-Dehydroamino Acid Derivatives: Facile Synthesis of Chiral beta-Hydroxy-alpha-amino Acids
16
Tunable Arylative Cyclization of 1,6-Enynes Triggered by Rhodium(III)-Catalyzed C-H Activation
15
Catalytic Asymmetric Conjugate Addition of alpha-Substituted Nitro Acetates to Nitro Olefins: Enantioselective Synthesis of Highly Substituted gamma-Lactams
14
Chiral NHC/Cu(I)-Catalyzed Asymmetric Hydroboration of Aldimines: Enantioselective Synthesis of alpha-Amido Boronic Esters
13
Cu-Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone-Containing 1,6-Enynes
12
Rhodium-Catalyzed Asymmetric Arylative Cyclization of meso-1,6-Dienynes Leading to Enantioenriched cis-Hydrobenzofurans
11
Separation of enantiopure m-substituted 1-phenylethanols in high space-time yield using Bacillus subtilis esterase
10
Stereoselective Total Synthesis of Tubulysin V
9
Zinc-Mediated Asymmetric Allylation of Chiral N-tert-Butanesulfinyl Aldimines with 3-Bromomethyl-5H-furan-2-one
8
Rhodium-Catalyzed Asymmetric Arylation
7
Rhodium/diene-catalyzed asymmetric arylation of N-Boc-protected α,β-unsaturated δ-lactam with arylboronic acids: enantioselective synthesis of 4-aryl-2-piperidinones
6
Asymmetric Synthesis of β-Substituted γ-Lactams via Rhodium/Diene-Catalyzed 1,4-Additions: Application to the Synthesis of (R)-Baclofen and (R)-Rolipram
5
Biscinchona alkaloids as highly efficient bifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroalkenes at ambient temperature
4
Easily Accessible C2‐Symmetric Chiral Bicyclo[3.3.0] Dienes as Ligands for Rhodium‐Catalyzed Asymmetric 1,4‐Addition
3
Lipase-Catalyzed Desymmetrization of Quaternary Carbon-Containing 1,3-Propanediols: A New Entry to the Asymmetric Synthesis of α-Substituted Serine Analogues
2
New β-amino alcohols with a bicyclo[3.3.0]octane scaffold in an asymmetric Henry reaction
1
Lipase‐Catalyzed Resolutions of both Enantiomers of Ornidazole and Secnidazole
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