田平 讲席教授, 博导, 副院长
手性药物研究中心
创新中药研究院
上海中医药大学
地址:上海市浦东新区蔡伦路1200号
电话:(+86)-21-5132 2765
邮箱:tianping@shutcm.edu.cn
or tianping@sioc.ac.cn
研究内容
合成方法导向多样性分子的生理活性研究
基于靶点或计算机辅助的药物设计
利用化学生物学阐述中药单体的作用机制研究
整合现代分子工程技术创制源于中药的新药研究
工作经历
2022−目前
研究员, 博导,上海中医药大学 创新中药研究院 副院长
2017−目前
研究员, 博导,上海中医药大学 创新中药研究院 手性药物研究中心
2010−2017
副研究员, 中国科学院 上海有机化学研究所 天然产物有机合成化学重点实验室
2006−2009
高级研究员, SynChem, Inc.
2005−2006
助研, 中国科学院 上海有机化学研究所 天然产物有机合成化学重点实验室
教育背景
1999−2005
博士, 中国科学院 上海有机化学研究所 (导师: 林国强 院士)
1995−1999
本科, 武汉大学 化学与分子科学学院 (导师: 李早英 教授)
学术荣誉
Thieme Chemistry Journal Awardees 2017
上海市高水平地方高校重点创新团队负责人 2017-2020
上海市优秀学术带头人 2020
上海市高水平地方高校重点创新团队负责人 2021-2024
上海中医药大学第三届“我心目中的好老师”2022
广慈-思南产医融合国际创新大赛“十佳医学创新成果入围奖” 2022
上海市浦东新区“明珠领军人才”2023
上海中医药大学优秀研究生导师 2023
代表性论文
13.Hao Xu,# Yun-Xuan Tan,# Pei-Pei Xie,# Rui Ding, Qi Liao, Jian-Wei Zhang, Qing-Hua Li,* Yu-Hui Wang,* Xin Hong,* Guo-Qiang Lin, and Ping Tian* Rhodium(III)-Catalyzed Asymmetric Reductive Cyclization of Cyclohexadienone-Containing 1,6-Dienes via an Anti-Michael/ Michael Cascade Process. ACS Catal. 2021, 11, 8015−8022. (IF = 12.350)
12.Chang-Yun Shi, Zhi-Zhou Pan, Ping Tian,* and Liang Yin* Copper(I)-catalyzed asymmetric 1,6-conjugate allylation. Nat. Commun. 2020, 11, 5480. (IF = 12.121)
11.Xu-Cheng Gan,# Cheng-Yuan Zhang,# Feng Zhong,# Ping Tian,* and Liang Yin* Synthesis of Chiral anti-1,2-Diamine Derivatives through Copper(I)-Catalyzed Asymmetric α-Addition of Ketimines to Aldimines. Nat. Commun. 2020, 11, 4473. (IF = 12.121)
10.Cheng-Yu He,# Yun-Xuan Tan,# Xin Wang, Rui Ding, Yi-Fan Wang, Feng Wang, Dingding Gao,* Ping Tian,* and Guo-Qiang Lin* Copper(I)-catalyzed Diastereo- and Enantio-selective Construction of Optically Pure Exocyclic Allenes. Nat. Commun. 2020, 11, 4293. (IF = 12.121)
9.Peng Yang,# Jian Li,# Li Sun, Ming Yao, Xiang Zhang, Wei-Lie Xiao, Jian-Hua Wang, Ping Tian,* Han-Dong Sun,* Pema-Tenzin Puno,* and Ang Li* Elucidation of the Structure of Pseudorubriflordilactone B by Chemical Synthesis. J. Am. Chem. Soc. 2020, 142, 13701–13708. (IF = 14.612)
8.Yu-Hui Wang,# Zhong-Yan Cao,# Qing-Hua Li, Guo-Qiang Lin, Jian Zhou,* and Ping Tian,* Activating Pronucleophiles with High pKa Values: Chiral Organo‐Superbases. Angew. Chem. Int. Ed. 2020, 59, 8004−8014. (IF = 12.959)
7.Xin Chen, Dingding Gao, Dong Wang, Tong Xu, Wei Liu, Ping Tian,* and Xiaofeng Tong,* Access to Aryl-Naphthaquinone Atropisomers via Phosphine-Catalyzed Atroposelective (4+2) Annulations of δ-Acetoxy Allenoates with 2-Hydroxyquinone Derivatives. Angew. Chem., Int. Ed. 2019, 58, 15334−15338. (IF = 12.959)
6.Yun-Xuan Tan, Fang Zhang, Pei-Pei Xie, Shuo-Qing Zhang, Yi-Fan Wang, Qing-Hua Li, Ping Tian,* Xin Hong,* and Guo-Qiang Lin,* Rhodium(III)-Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone-Containing 1,6-Dienes: An Experimental and DFT Study. J. Am. Chem. Soc. 2019, 141, 12770−12779. (IF = 14.612)
5.Zhi-Tao He, Xiao-Qi Tang, Li-Bo Xie, Mian Cheng, Ping Tian,* and Guo-Qiang Lin, Efficient Access to Bicyclo[4.3.0]nonanes: Cu-Catalyzed Asymm-etric Silylative Cyclization of Cyclohexadienone-tethered Allenes. Angew. Chem. Int. Ed. 2015, 54, 14815−14818. (IF = 12.959)
4.Yuki Fukui,# Ping Liu,# Qiang Liu, Zhi-Tao He, Nuo-Yi Wu, Ping Tian,* and Guo-Qiang Lin,* Tunable Arylative Cyclization of 1,6-Enynes Triggered by Rhodium(III)-Catalyzed C−H Activation. J. Am. Chem. Soc. 2014, 136, 15607−15614. (IF = 14.612)
3.Ping Liu, Yuki Fukui, Ping Tian,* Zhi-Tao He, Cai-Yun Sun, Nuo-Yi Wu, and Guo-Qiang Lin,* Cu-Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone-Containing 1,6-Enynes. J. Am. Chem. Soc. 2013, 135, 11700−11704. (IF = 14.612)
2.Zhi-Tao He, Bing Tian, Yuki Fukui, Xiaofeng Tong, Ping Tian,* and Guo-Qiang Lin,* Rhodium-Catalyzed Asymmetric Arylative Cyclization of meso-1,6-Dienynes Leading to Enantioenriched cis-Hydrobenzofurans. Angew. Chem. Int. Ed. 2013, 52, 5314−5318. (IF = 12.959)
1.Ping Tian, Han-Qing Dong, and Guo-Qiang Lin,* Rhodium-Catalyzed Asymmetric Arylation. ACS Catal. 2012, 2, 95−119. (IF = 12.350, Top 1% Cited Papers)