2021.1−目前

副研究员, 上海中医药大学创新中药研究院 手性药物研究中心

2023.4−2024.4

Visiting Scientist，哈佛大学医学院，Dana-Farber Cancer Institute

2020.7−2020.12

助理研究员, 上海中医药大学 创新中药研究院 手性药物研究中心

2018.7−2020.6

师资博士后, 上海中医药大学 合作导师：林国强 研究员（院士）

2012.9-2018.6

博士，复旦大学药学院 （导师：李英霞 教授）

2008.9−2012.7

本科，郑州大学药学院

上海市白玉兰人才计划浦江项目（原上海市浦江人才）2024

上海市浦东新区“明珠菁英人才”2024

上海中医药大学“杏林青年学者” 2020

上海中医药大学“十大杏林菁英” 2020

上海市青年科技英才“扬帆计划” 2019

1. 上海市白玉兰计划浦江项目（24PJD109，2024.12-2026.11）

2. 上海中医药大学科技发展项目（24KFL035，2024.11-2026.10）

3. 上海市手性药物分子工程重点实验室开放课题（2022.01-2023.12）

4.  国家自然科学基金青年基金（81903423，2020.01−2022.12）

5. 上海市青年科技英才扬帆计划（19YF1449300，2019.05−2022.04）

6.  中国博士后科学基金面上项目（2018M642064，2018.11-2020.07）

7. 上海中医药大学预算内项目（A1-GY0309，2019.01-2020.12）

15. Feng Wang,# Donglan Liu,# Dingding Gao,* Jinwei Yuan, Jingxian Zhao, Shuai Yuan, Yixin Cen,* Guo-Qiang Lin,* Jincun Zhao,* and Ping Tian*   Discovery of natural catechol derivatives as covalent SARS-CoV-2 3CL^pro inhibitors. Int. J. Biol. Macromol.  2024, 264, 130377. (IF 8.2)

14. Qing-Hua Li,# Gui-Shan Zhang,# Feng Wang, Yixin Cen, Xi-Liang Liu, Jian-Wei Zhang, Yu-Hui Wang,* Albert W. M. Lee,* Dingding Gao,* Guo-Qiang Lin, and Ping Tian*   Nature-Inspired Catalytic Asymmetric Rearrangement of Cyclopropylcarbinyl Cation. Sci. Adv.  2023, 9, eadg1237. (IF 13.6)

13. Dingding Gao,#* Shuai Tang,# Yixin Cen,# Liang Yuan, Xiaojing Lan, Qing-Hua Li,* Guo-Qiang Lin, Min Huang,* and Ping Tian*   Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy. J. Med. Chem.  2023, 66, 285. (IF 7.3)

12. Jian-Wei Zhang,# Yuan Xiong,# Feng Wang, Fu-Mao Zhang, Xiaodi Yang, Guo-Qiang Lin, Ping Tian,* Guangbo Ge,* and Dingding Gao*   Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CL^pro inhibitors for treating COVID-19. Eur. J. Med. Chem.  2022, 228, 114030. (IF 7.088)

11. Jia-Ying Zhao, Kai-Rui Feng, Feng Wang, Jian-Wei Zhang, Jay Fei Cheng,* Guo-Qiang Lin, Dingding Gao,* and Ping Tian*   A Retrospective Overview of PHGDH and Its Inhibitors for Regulating Cancer Metabolism. Eur. J. Med. Chem.  2021, 217, 113379. (IF 5.572)

10. Qing-Hua Li,# Dingding Gao,# Cheng-Yu He, Qi Liao, Yun-Xuan Tan, Yu-Hui Wang,* Rui Ding,* Guo-Qiang Lin, and Ping Tian*   One-Pot Preparation of Bridged Tricyclic and Fused Tetracyclic Scaffolds via Rhodium(III)-Catalyzed Asymmetric Borylative Cyclization. Cell Reports Physical Science 2020,1, 100222.

9.Cheng-Yu He#, Yun-Xuan Tan#, Xin Wang, Rui Ding, Yi-Fan Wang, Feng Wang, Dingding Gao*, Ping Tian *, and Guo-Qiang Lin*  Copper(I)-Catalyzed Diastereo- and Enantioselective Construction of Optically Pure Exocyclic Allenes. Nat. Commun. 2020, 11, 4293. (IF 12.121)

8.Dingding Gao#, Xing-Yu Liu#, Hao Xu#, Yun-Xuan Tan, Qi Liao, Qing-Hua Li*, Xiaodi Yang, Guo-Qiang Lin*, and Ping Tian*  One-Pot Preparation of 9,10-Dihydrophenanthrenes Initiated by Rhodium(III)-Catalyzed C−H Activation and Relay Diels-Alder Reaction. Org. Lett. 2020, 22, 4300−4305. (IF 6.091)

7.Kai-Rui Feng#, Feng Wang#, Xin-Wei Shi, Yun-Xuan Tan, Jia-Ying Zhao, Jian-Wei Zhang, Qing-Hua Li*, Guo-Qiang Lin, Dingding Gao*, and Ping Tian*  Design, synthesis and biological evaluation of novel potent STAT3 inhibitors based on BBI608 for cancer therapy. Eur. J. Med. Chem., 2020, 201, 112428. (IF 5.572)

6.Dingding Gao#, Feng Wang#, Xing-Yu Liu, Kai-Rui Feng, Jia-Ying Zhao, Yu-Hui Wang*, Xiao-Di Yang*, Ping Tian*, and Guo-Qiang Lin  Synthesis of Decahydrocyclobuta[cd]indene Skeleton: Rhodium(III)-Catalyzed Hydroarylaton and Relay Thiophene-Promoted Intramolecular [2 + 2] Cycloaddition. Adv. Synth. Catal. 2020, 362, 4384–4390. (IF 5.851)

5.Jun-Li Zhang#, Dingding Gao#, Yun-Xuan Tan, Cheng-Yu He, Pei-Ying Peng, Guo-Qiang Lin, Qing-Hua Li*, Ping Tian*  Rhodium(III)-Catalyzed Kinetic Resolution of Racemic 1,6-Dienes via Asymmetric Borylative Cyclization. Org. Lett. 2020, 22, 3661-3666. (IF 6.091)

4.Ming-Shun Mei#, Yu-Hui Wang#, Qing Hu, Qing-Hua Li, Da-Yu Shi, Dingding Gao,* Guangbo Ge,* Guo-Qiang Lin, and Ping Tian*   Enantioselective [3 + 2] Annulation of Isatin-Derived MBH-Carbonates and 3-Nitroindoles Enabled by a Bifunctional DMAP-Thiourea. Chem. Commun. 2020, 56, 10718-10721. (IF 5.996)

3.Bingbing Zhang#, Jiami Liu#, Dingding Gao#, Xiaolin Yu, Jinlei Wang, Xinsheng Lei*  A fluorine scan on the Zn2+-binding thiolate side chain of HDAC inhibitor largazole: Synthesis, biological evaluation, and molecular modeling. Eur. J. Med. Chem. 2019, 182, 111672. (IF 5.572)

2.Dingding Gao#, Huixia Dou#, Haixia Su#, Mingming Zhang#, Ting Wang, Qiufeng Liu, Haiyan Cai, Zhuo Yang, Weiliang Zhu*, Yechun Xu*, Heyao Wang*, Yingxia Li*  From Hit to Lead: Structure-based Discovery of Naphthalene-1-Sulfonamide Derivatives as Potent and Selective Inhibitors of Fatty Acid Binding Protein 4. Eur. J. Med. Chem. 2018, 154, 44-59. (IF 5.572)

1.Haiyan Cai#, Qiufeng Liu#, Dingding Gao#, Ting Wang, Tiantian Chen,Guirui Yan, Kaixian Chen, Yechun Xu*, Heyao Wang*, Yingxia Li*, Weiliang Zhu*  Novel fatty acid binding protein 4 (FABP4) inhibitors: Virtual screening, synthesis and crystal structure determination. Eur. J. Med. Chem. 2015, 90, 241-250. (IF 5.572)