王雨卉 博士 副研究员

创新中药研究院 手性药物研究中心

上海中医药大学

地址:上海市浦东新区蔡伦路1200号

电话:(+86)-21-5132 8495

邮箱:wangyuhui@shutcm.edu.cn

  • 研究内容

    • 不对称催化

    • 有机合成

  • 教育背景

    • 2013.9-2018.6

      博士,华东师范大学,有机化学专业 (导师:周剑 教授)

    • 2009.9-2013.6

      本科,华东师范大学,应用化学专业 (导师:周剑 教授)

  • 工作经历

    • 2021.1−目前

      副研究员,上海市中医药大学 创新中药研究院 手性药物研究中心

    • 2020.7−2020.12

      助理研究员,上海市中医药大学 创新中药研究院 手性药物研究中心

    • 2018.6-2020.6

      师资博士后,上海中医药大学,中药学专业, 合作导师:林国强 研究员(院士)

  • 学术荣誉

    • 上海中医药大学“杏林青年学者” 2020                    

    • 上海市青年科技英才“扬帆计划” 2020

    • 上海市教育委员会“晨光计划” 2020

  • 主持科研项目

    • 1. 上海市自然科学基金面上项目(24ZR1466400,2024.102027.9)

    • 2. 国家自然科学基金青年基金(22001172,2021.012023.12)

    • 3. 上海市教育委员会“晨光计划”(20CG52,2021.012022.12)

    • 4. 上海市青年科技英才“扬帆计划”(20YF1449300,2020.072023.06)

  • 代表性论文

    • 8.Hao Xu,# Yun-Xuan Tan,# Pei-Pei Xie,# Rui Ding, Qi Liao, Jian-Wei Zhang, Qing-Hua Li,* Yu-Hui Wang,* Xin Hong,* Guo-Qiang Lin, and Ping Tian*  Rhodium(III)-Catalyzed Asymmetric Reductive Cyclization of Cyclohexadienone-Containing 1,6-Dienes via an Anti-Michael/ Michael Cascade Process. ACS Catal. 2021, 11, 8015−8022. (IF = 12.350)

    • 7.Ming-Shun Mei, Ya-Jie Wang, Gui-Shan Zhang, Jing-Yi Tang*, Ping Tian*, and Yu-Hui Wang*  Catalyst-Controlled Diastereoselectivity Switch in the Asymmetric [3+2] Annulation of Isatin-Derived MBH Carbonates and 5-Alkenylthiazol-4(5H)-ones. Org. Lett. 202123, 7336−7341. (IF = 6.005)

    • 6.Yu-Hui Wang,# Zhong-Yan Cao,# Qing-Hua Li, Guo-Qiang Lin, Jian Zhou,* and Ping Tian*  Activating Pronucleophiles with High pKa Values: Chiral Organo‐Superbases. Angew. Chem. Int. Ed. 202059, 8004−8014. (IF = 12.959)

    • 5.Yu‐Hui Wang, Jun‐Song Tian, Peng‐Wei Tan, Qiang Cao, Xue‐Xin Zhang, Zhong‐Yan Cao, Feng Zhou, Xin Wang,*  and Jian Zhou* Regiodivergent Intramolecular Nucleophilic Addition of Ketimines for the Diverse Synthesis of Azacycles. Angew. Chem. Int. Ed. 202059, 1634−1643. (IF = 12.959)

    • 4.Qing-Hua Li,# Dingding Gao,# Cheng-Yu He, Qi Liao, Yun-Xuan Tan, Yu-Hui Wang,* Rui Ding,* Guo-Qiang Lin, and Ping Tian*   One-Pot Preparation of Bridged Tricyclic and Fused Tetracyclic Scaffolds via Rhodium(III)-Catalyzed Asymmetric Borylative Cyclization. Cell Reports Physical Science 20201, 100222.

    • 3.Xing-Yu Liu, Yun-Xuan Tan, Xin Wang, Hao Xu, Yu-Hui Wang,* Ping Tian,* and Guo-Qiang Lin*  Nickel(II)-Catalyzed Addition of Aryl-, Alkenyl-, and Alkylboronic Acids to Alkenylazaarenes  Org. Lett. 2020,  22, 4038−4042. (IF 6.091)

    • 2.Ming-Shun Mei#, Yu-Hui Wang#, Qing Hu, Qing-Hua Li,Da-Yu Shi, Dingding Gao,* Guangbo Ge,* Guo-Qiang Lin, and Ping Tian*   Enantioselective [3 + 2] Annulation of Isatin-Derived MBH-Carbonates and 3-Nitroindoles Enabled by a Bifunctional DMAP-Thiourea. Chem. Commun. 202056, 10718-10721. (IF 5.996)

    • 1.Dingding Gao#, Feng Wang#, Xing-Yu Liu, Kai-Rui Feng, Jia-Ying Zhao, Yu-Hui Wang*, Xiao-Di Yang*, Ping Tian*, and Guo-Qiang Lin  Synthesis of Decahydrocyclobuta[cd]indene Skeleton: Rhodium(III)-Catalyzed Hydroarylaton and Relay Thiophene-Promoted Intramolecular [2 + 2] Cycloaddition. Adv. Synth. Catal. 2020362, 4384–4390. (IF 5.851)